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Non-coding roX RNAs Prevent the Binding of the MSL-complex to Heterochromatic Regions

Long non-coding RNAs contribute to dosage compensation in both mammals and Drosophila by inducing changes in the chromatin structure of the X-chromosome. In Drosophila melanogaster, roX1 and roX2 are long non-coding RNAs that together with proteins form the male-specific lethal (MSL) complex, which...

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Detalles Bibliográficos
Autores principales: Figueiredo, Margarida L. A., Kim, Maria, Philip, Philge, Allgardsson, Anders, Stenberg, Per, Larsson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263465/
https://www.ncbi.nlm.nih.gov/pubmed/25501352
http://dx.doi.org/10.1371/journal.pgen.1004865