Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants

We demonstrate that the purified Staphylococcus aureus extracellular proteases aureolysin, ScpA, SspA, and SspB limit biofilm formation, with aureolysin having the greatest impact. Using protease-deficient derivatives of LAC, we confirmed that this is due to the individual proteases themselves. Puri...

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Detalles Bibliográficos
Autores principales: Loughran, Allister J, Atwood, Danielle N, Anthony, Allison C, Harik, Nada S, Spencer, Horace J, Beenken, Karen E, Smeltzer, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263513/
https://www.ncbi.nlm.nih.gov/pubmed/25257373
http://dx.doi.org/10.1002/mbo3.214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263513/
https://www.ncbi.nlm.nih.gov/pubmed/25257373
http://dx.doi.org/10.1002/mbo3.214

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