Functionally Selective Signaling for Morphine and Fentanyl Antinociception and Tolerance Mediated by the Rat Periaqueductal Gray

Functionally selective signaling appears to contribute to the variability in mechanisms that underlie tolerance to the antinociceptive effects of opioids. The present study tested this hypothesis by examining the contribution of G protein-coupled receptor kinase (GRK)/Protein kinase C (PKC) and C-Ju...

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Detalles Bibliográficos
Autores principales: Morgan, Michael M., Reid, Rachel A., Saville, Kimber A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263532/
https://www.ncbi.nlm.nih.gov/pubmed/25503060
http://dx.doi.org/10.1371/journal.pone.0114269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263532/
https://www.ncbi.nlm.nih.gov/pubmed/25503060
http://dx.doi.org/10.1371/journal.pone.0114269

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