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Linking Single Domain Antibodies that Recognize Different Epitopes on the Same Target

Single domain antibodies (sdAb) are the recombinantly expressed variable regions from the heavy-chain-only antibodies found in camelids and sharks. SdAb are able to bind antigens with high affinity, and most are capable of refolding after heat or chemical denaturation to bind antigen again. Starting...

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Detalles Bibliográficos
Autores principales: Glaven, Richard H., Anderson, George P., Zabetakis, Dan, Liu, Jinny L., Long, Nina C., Goldman, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263546/
https://www.ncbi.nlm.nih.gov/pubmed/25585631
http://dx.doi.org/10.3390/bios2010043