Role of the ubiquitin–proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

Systemic deletion of the gene encoding for adipose triglyceride lipase (ATGL) in mice leads to severe cardiac dysfunction due to massive accumulation of neutral lipids in cardiomyocytes. Recently, impaired peroxisome proliferator-activated receptor α (PPARα) signaling has been described to substanti...

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Detalles Bibliográficos
Autores principales: Mussbacher, Marion, Stessel, Heike, Wölkart, Gerald, Haemmerle, Guenter, Zechner, Rudolf, Mayer, Bernd, Schrammel, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263609/
https://www.ncbi.nlm.nih.gov/pubmed/25285770
http://dx.doi.org/10.1016/j.yjmcc.2014.09.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263609/
https://www.ncbi.nlm.nih.gov/pubmed/25285770
http://dx.doi.org/10.1016/j.yjmcc.2014.09.028

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