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Role of the ubiquitin–proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice
Systemic deletion of the gene encoding for adipose triglyceride lipase (ATGL) in mice leads to severe cardiac dysfunction due to massive accumulation of neutral lipids in cardiomyocytes. Recently, impaired peroxisome proliferator-activated receptor α (PPARα) signaling has been described to substanti...
Autores principales: | Mussbacher, Marion, Stessel, Heike, Wölkart, Gerald, Haemmerle, Guenter, Zechner, Rudolf, Mayer, Bernd, Schrammel, Astrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263609/ https://www.ncbi.nlm.nih.gov/pubmed/25285770 http://dx.doi.org/10.1016/j.yjmcc.2014.09.028 |
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