High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis

With the goal to generate and characterize the phenotypes of null alleles in all genes within an organism and the recent advances in custom nucleases, genome editing limitations have moved from mutation generation to mutation detection. We previously demonstrated that High Resolution Melting (HRM) a...

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Detalles Bibliográficos
Autores principales: Thomas, Holly R., Percival, Stefanie M., Yoder, Bradley K., Parant, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263700/
https://www.ncbi.nlm.nih.gov/pubmed/25503746
http://dx.doi.org/10.1371/journal.pone.0114632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263700/
https://www.ncbi.nlm.nih.gov/pubmed/25503746
http://dx.doi.org/10.1371/journal.pone.0114632

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