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Unexpected DNA Loss Mediated by the DNA Binding Activity of Ribonuclease A
Ribonuclease A (RNase A) is widely used in molecular biology research both for analytical assays and for nucleic acid preparation. The catalytic mechanism of RNase A is well understood and absolutely precludes activity on DNA; however anecdotal reports of DNA degradation by RNase A are not uncommon....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263722/ https://www.ncbi.nlm.nih.gov/pubmed/25502562 http://dx.doi.org/10.1371/journal.pone.0115008 |