Functional Upregulation of Nav1.8 Sodium Channels on the Membrane of Dorsal Root Ganglia Neurons Contributes to the Development of Cancer-Induced Bone Pain

We have previously reported that enhanced excitability of dorsal root ganglia (DRG) neurons contributes to the development of bone cancer pain, which severely decreases the quality of life of cancer patients. Nav1.8, a tetrodotoxin-resistant (TTX-R) sodium channel, contributes most of the sodium cur...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Dan, Yang, Jing-Jing, Fang, Dong, Cai, Jie, Wan, You, Xing, Guo-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263726/
https://www.ncbi.nlm.nih.gov/pubmed/25503076
http://dx.doi.org/10.1371/journal.pone.0114623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263726/
https://www.ncbi.nlm.nih.gov/pubmed/25503076
http://dx.doi.org/10.1371/journal.pone.0114623

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