Abieslactone Induces Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinomas through the Mitochondrial Pathway and the Generation of Reactive Oxygen Species

Abieslactone is a triterpenoid lactone isolated from Abies plants. Previous studies have demonstrated that its derivative abiesenonic acid methyl ester possesses anti-tumor-promoting activity in vitro and in vivo. In the present study, cell viability assay demonstrated that abieslactone had selectiv...

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Detalles Bibliográficos
Autores principales: Wang, Guo-Wei, Lv, Chao, Shi, Zhi-Ran, Zeng, Ren-Tao, Dong, Xue-Yun, Zhang, Wei-Dong, Liu, Run-Hui, Shan, Lei, Shen, Yun-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263740/
https://www.ncbi.nlm.nih.gov/pubmed/25502685
http://dx.doi.org/10.1371/journal.pone.0115151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263740/
https://www.ncbi.nlm.nih.gov/pubmed/25502685
http://dx.doi.org/10.1371/journal.pone.0115151

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