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Abieslactone Induces Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinomas through the Mitochondrial Pathway and the Generation of Reactive Oxygen Species

Abieslactone is a triterpenoid lactone isolated from Abies plants. Previous studies have demonstrated that its derivative abiesenonic acid methyl ester possesses anti-tumor-promoting activity in vitro and in vivo. In the present study, cell viability assay demonstrated that abieslactone had selectiv...

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Detalles Bibliográficos
Autores principales:	Wang, Guo-Wei, Lv, Chao, Shi, Zhi-Ran, Zeng, Ren-Tao, Dong, Xue-Yun, Zhang, Wei-Dong, Liu, Run-Hui, Shan, Lei, Shen, Yun-Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263740/ https://www.ncbi.nlm.nih.gov/pubmed/25502685 http://dx.doi.org/10.1371/journal.pone.0115151

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