Cargando…

Hypercytotoxicity and Rapid Loss of NKp44(+) Innate Lymphoid Cells during Acute SIV Infection

HIV/SIV infections break down the integrity of the gastrointestinal mucosa and lead to chronic immune activation and associated disease progression. Innate lymphoid cells (ILCs), distinguishable by high expression of NKp44 and RORγt, play key roles in mucosal defense and homeostasis, but are deplete...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Haiying, Richert-Spuhler, Laura E., Evans, Tristan I., Gillis, Jacqueline, Connole, Michelle, Estes, Jacob D., Keele, Brandon F., Klatt, Nichole R., Reeves, R. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263758/
https://www.ncbi.nlm.nih.gov/pubmed/25503264
http://dx.doi.org/10.1371/journal.ppat.1004551