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Hypercytotoxicity and Rapid Loss of NKp44(+) Innate Lymphoid Cells during Acute SIV Infection
HIV/SIV infections break down the integrity of the gastrointestinal mucosa and lead to chronic immune activation and associated disease progression. Innate lymphoid cells (ILCs), distinguishable by high expression of NKp44 and RORγt, play key roles in mucosal defense and homeostasis, but are deplete...
Autores principales: | Li, Haiying, Richert-Spuhler, Laura E., Evans, Tristan I., Gillis, Jacqueline, Connole, Michelle, Estes, Jacob D., Keele, Brandon F., Klatt, Nichole R., Reeves, R. Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263758/ https://www.ncbi.nlm.nih.gov/pubmed/25503264 http://dx.doi.org/10.1371/journal.ppat.1004551 |
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