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IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza

Influenza is a major cause of morbidity and mortality in immunosuppressed persons, and vaccination often confers insufficient protection. IL-28B, a member of the interferon (IFN)-λ family, has variable expression due to single nucleotide polymorphisms (SNPs). While type-I IFNs are well known to modu...

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Detalles Bibliográficos
Autores principales: Egli, Adrian, Santer, Deanna M., O'Shea, Daire, Barakat, Khaled, Syedbasha, Mohammedyaseen, Vollmer, Madeleine, Baluch, Aliyah, Bhat, Rakesh, Groenendyk, Jody, Joyce, Michael A., Lisboa, Luiz F., Thomas, Brad S., Battegay, Manuel, Khanna, Nina, Mueller, Thomas, Tyrrell, D. Lorne J., Houghton, Michael, Humar, Atul, Kumar, Deepali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263767/
https://www.ncbi.nlm.nih.gov/pubmed/25503988
http://dx.doi.org/10.1371/journal.ppat.1004556