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A Low-Noise Solid-State Nanopore Platform Based on a Highly Insulating Substrate

A solid-state nanopore platform with a low noise level and sufficient sensitivity to discriminate single-strand DNA (ssDNA) homopolymers of poly-A(40) and poly-T(40) using ionic current blockade sensing is proposed and demonstrated. The key features of this platform are (a) highly insulating dielect...

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Detalles Bibliográficos
Autores principales: Lee, Min-Hyun, Kumar, Ashvani, Park, Kyeong-Beom, Cho, Seong-Yong, Kim, Hyun-Mi, Lim, Min-Cheol, Kim, Young-Rok, Kim, Ki-Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264027/
https://www.ncbi.nlm.nih.gov/pubmed/25502421
http://dx.doi.org/10.1038/srep07448