Sox2-Mediated Conversion of NG2 Glia into Induced Neurons in the Injured Adult Cerebral Cortex

The adult cerebral cortex lacks the capacity to replace degenerated neurons following traumatic injury. Conversion of nonneuronal cells into induced neurons has been proposed as an innovative strategy toward brain repair. Here, we show that retrovirus-mediated expression of the transcription factors...

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Detalles Bibliográficos
Autores principales: Heinrich, Christophe, Bergami, Matteo, Gascón, Sergio, Lepier, Alexandra, Viganò, Francesca, Dimou, Leda, Sutor, Bernd, Berninger, Benedikt, Götz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264057/
https://www.ncbi.nlm.nih.gov/pubmed/25458895
http://dx.doi.org/10.1016/j.stemcr.2014.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264057/
https://www.ncbi.nlm.nih.gov/pubmed/25458895
http://dx.doi.org/10.1016/j.stemcr.2014.10.007

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