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Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Overexpression of transcription factors has been used to directly reprogram somatic cells into a range of other differentiated cell types, including multipotent neural stem cells (NSCs), that can be used to generate neurons and glia. However, the ability to maintain the NSC state independent of the...

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Detalles Bibliográficos
Autores principales: Cassady, John P., D’Alessio, Ana C., Sarkar, Sovan, Dani, Vardhan S., Fan, Zi Peng, Ganz, Kibibi, Roessler, Reinhard, Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264067/
https://www.ncbi.nlm.nih.gov/pubmed/25454632
http://dx.doi.org/10.1016/j.stemcr.2014.10.001