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Catalpol Suppresses Proliferation and Facilitates Apoptosis of OVCAR-3 Ovarian Cancer Cells through Upregulating MicroRNA-200 and Downregulating MMP-2 Expression

Catalpol is expected to possess diverse pharmacological actions including anti-cancer, anti-inflammatory and hypoglycemic properties. Matrix metalloproteinase-2 (MMP-2) is closely related to the pathogenesis of ovarian cancer. In addition, microRNA-200 (miR-200) can modulate phenotype, proliferation...

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Detalles Bibliográficos
Autores principales: Gao, Na, Tian, Jian-Xin, Shang, Yu-Hong, Zhao, Dan-Yi, Wu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264118/
https://www.ncbi.nlm.nih.gov/pubmed/25347277
http://dx.doi.org/10.3390/ijms151119394