Obligatory Role of Intraluminal O(2)(−) in Acute Endothelin-1 and Angiotensin II Signaling to Mediate Endothelial Dysfunction and MAPK Activation in Guinea-Pig Hearts

We hypothesized that, due to a cross-talk between cytoplasmic O(2)(−)-sources and intraluminally expressed xanthine oxidase (XO), intraluminal O(2)(−) is instrumental in mediating intraluminal (endothelial dysfunction) and cytosolic (p38 and ERK1/2 MAPKs phosphorylation) manifestations of vascular o...

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Detalles Bibliográficos
Autores principales: Wojtera, Emilia, Konior, Anna, Fedoryszak-Kuśka, Natalia, Beręsewicz, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264120/
https://www.ncbi.nlm.nih.gov/pubmed/25350109
http://dx.doi.org/10.3390/ijms151119417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264120/
https://www.ncbi.nlm.nih.gov/pubmed/25350109
http://dx.doi.org/10.3390/ijms151119417

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