Cargando…

Validation of Bmi1 as a Therapeutic Target of Hepatocellular Carcinoma in Mice

Bmi1 is a member of the polycomb group family of proteins, and it drives the carcinogenesis of various cancers and governs the self-renewal of multiple types of stem cells. Our previous studies have revealed that Bmi1 acts as an oncogene in hepatic carcinogenesis in an INK4a/ARF locus independent ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Shibo, Li, Bin, Yang, Tan, Liu, Yong, Cao, Shanshan, He, Xingxing, Zhang, Peng, Li, Lei, Xu, Chuanrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264152/
https://www.ncbi.nlm.nih.gov/pubmed/25372945
http://dx.doi.org/10.3390/ijms151120004