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Role of NADPH Oxidase and Xanthine Oxidase in Mediating Inducible VT/VF and Triggered Activity in a Canine Model of Myocardial Ischemia

Background: Ventricular tachycardia or fibrillation (VT/VF) of focal origin due to triggered activity (TA) from delayed afterdepolarizations (DADs) is reproducibly inducible after anterior coronary artery occlusion. Both VT/VF and TA can be blocked by reducing reactive oxygen species (ROS). We teste...

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Detalles Bibliográficos
Autores principales: Martins, James B., Chaudhary, Ashok K., Jiang, Shuxia, Kwofie, Michael, Mackie, Prescott, Miller, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264157/
https://www.ncbi.nlm.nih.gov/pubmed/25375191
http://dx.doi.org/10.3390/ijms151120079