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Pressure Overload-Induced Cardiac Hypertrophy Response Requires Janus Kinase 2-Histone Deacetylase 2 Signaling

Pressure overload induces cardiac hypertrophy through activation of Janus kinase 2 (Jak2), however, the underlying mechanisms remain largely unknown. In the current study, we tested whether histone deacetylase 2 (HDAC2) was involved in the process. We found that angiotensin II (Ang-II)-induced re-ex...

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Detalles Bibliográficos
Autores principales: Ying, Huang, Xu, Mao-Chun, Tan, Jing-Hua, Shen, Jing-Hua, Wang, Hao, Zhang, Dai-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264164/
https://www.ncbi.nlm.nih.gov/pubmed/25380525
http://dx.doi.org/10.3390/ijms151120240