Structural Biology of DNA (6-4) Photoproducts Formed by Ultraviolet Radiation and Interactions with Their Binding Proteins

Exposure to the ultraviolet component of sunlight causes DNA damage, which subsequently leads to mutations, cellular transformation, and cell death. DNA photoproducts with (6-4) pyrimidine-pyrimidone adducts are more mutagenic than cyclobutane pyrimidine dimers. These lesions must be repaired becaus...

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Detalles Bibliográficos
Autores principales: Yokoyama, Hideshi, Mizutani, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264169/
https://www.ncbi.nlm.nih.gov/pubmed/25383676
http://dx.doi.org/10.3390/ijms151120321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264169/
https://www.ncbi.nlm.nih.gov/pubmed/25383676
http://dx.doi.org/10.3390/ijms151120321

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