Palmitic Acid-Induced Neuron Cell Cycle G(2)/M Arrest and Endoplasmic Reticular Stress through Protein Palmitoylation in SH-SY5Y Human Neuroblastoma Cells

Obesity-related neurodegenerative diseases are associated with elevated saturated fatty acids (SFAs) in the brain. An increase in SFAs, especially palmitic acid (PA), triggers neuron cell apoptosis, causing cognitive function to deteriorate. In the present study, we focused on the specific mechanism...

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Detalles Bibliográficos
Autores principales: Hsiao, Yung-Hsuan, Lin, Ching-I, Liao, Hsiang, Chen, Yue-Hua, Lin, Shyh-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264201/
https://www.ncbi.nlm.nih.gov/pubmed/25402647
http://dx.doi.org/10.3390/ijms151120876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264201/
https://www.ncbi.nlm.nih.gov/pubmed/25402647
http://dx.doi.org/10.3390/ijms151120876

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