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3,4,5-Trichloroaniline Nephrotoxicity in Vitro: Potential Role of Free Radicals and Renal Biotransformation

Chloroanilines are widely used in the manufacture of drugs, pesticides and industrial intermediates. Among the trichloroanilines, 3,4,5-trichloroaniline (TCA) is the most potent nephrotoxicant in vivo. The purpose of this study was to examine the nephrotoxic potential of TCA in vitro and to determin...

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Detalles Bibliográficos
Autores principales: Racine, Christopher, Ward, Dakota, Anestis, Dianne K., Ferguson, Travis, Preston, Deborah, Rankin, Gary O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264202/
https://www.ncbi.nlm.nih.gov/pubmed/25402648
http://dx.doi.org/10.3390/ijms151120900