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Inhibition of Histone Deacetylase by Butyrate Protects Rat Liver from Ischemic Reperfusion Injury

We showed previously that pretreatment of butyrate, which is an endogenous histone deacetylase (HDAC) inhibitor normally fermented from undigested fiber by intestinal microflora, seriously alleviated ischemia reperfusion (I/R)-induced liver injury by inhibiting the nuclear factor κB (NF-κB) pathway....

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Detalles Bibliográficos
Autores principales: Sun, Jie, Wu, Qiujv, Sun, Huiling, Qiao, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264212/
https://www.ncbi.nlm.nih.gov/pubmed/25405737
http://dx.doi.org/10.3390/ijms151121069