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Inhibition of p53 deSUMOylation Exacerbates Puromycin Aminonucleoside-Induced Apoptosis in Podocytes

Apoptosis is a major cause of reduced podocyte numbers, which leads to proteinuria and/or glomerulosclerosis. Emerging evidence has indicated that deSUMOylation, a dynamic post-translational modification that reverses SUMOylation, is involved in the apoptosis of Burkitt’s lymphoma cells and cardiomy...

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Detalles Bibliográficos
Autores principales: Wang, Lingyu, Zhu, Jingwei, Fang, Ming, Zhang, Tuaner, Xie, Hua, Wang, Nan, Shen, Nan, Guo, Hui, Fu, Bo, Lin, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264227/
https://www.ncbi.nlm.nih.gov/pubmed/25411797
http://dx.doi.org/10.3390/ijms151121314