Androgen Receptor Antagonists and Anti-Prostate Cancer Activities of Some Newly Synthesized Substituted Fused Pyrazolo-, Triazolo- and Thiazolo-Pyrimidine Derivatives

A series of substituted pyrazole, triazole and thiazole derivatives (2–13) were synthesized from 1-(naphtho[1,2-d]thiazol-2-yl)hydrazine as starting material and evaluated as androgen receptor antagonists and anti-prostate cancer agents. The newly synthesized compounds showed potent androgen recepto...

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Detalles Bibliográficos
Autores principales: Bahashwan, Saleh A., Fayed, Ahmed A., Ramadan, Mohamed A., Amr, Abd El-Galil E., Al-Harbi, Naif O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264242/
https://www.ncbi.nlm.nih.gov/pubmed/25421248
http://dx.doi.org/10.3390/ijms151121587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264242/
https://www.ncbi.nlm.nih.gov/pubmed/25421248
http://dx.doi.org/10.3390/ijms151121587

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