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Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: a retrospective cohort study

INTRODUCTION: The impact of in vitro resistance on initially appropriate antibiotic therapy (IAAT) remains unclear. We elucidated the relationship between non-IAAT and mortality, and between IAAT and multi-drug resistance (MDR) in sepsis due to Gram-negative bacteremia (GNS). METHODS: We conducted a...

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Detalles Bibliográficos
Autores principales: Zilberberg, Marya D, Shorr, Andrew F, Micek, Scott T, Vazquez-Guillamet, Cristina, Kollef, Marin H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264255/
https://www.ncbi.nlm.nih.gov/pubmed/25412897
http://dx.doi.org/10.1186/s13054-014-0596-8