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K(r)/K(c) but not d(N)/d(S) correlates positively with body mass in birds, raising implications for inferring lineage-specific selection
BACKGROUND: The ratio of the rates of non-synonymous and synonymous substitution (d(N)/d(S)) is commonly used to estimate selection in coding sequences. It is often suggested that, all else being equal, d(N)/d(S) should be lower in populations with large effective size (N(e)) due to increased effica...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264323/ https://www.ncbi.nlm.nih.gov/pubmed/25607475 http://dx.doi.org/10.1186/s13059-014-0542-8 |