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Inhibition of triple-negative and Herceptin-resistant breast cancer cell proliferation and migration by Annexin A2 antibodies

BACKGROUND: Annexin A2 (AnxA2), a calcium-dependent phospholipid binding protein, is abundantly present at the surface of triple-negative and Herceptin-resistant breast cancer cells. Interactions between cell-surface AnxA2 and tyrosine kinase receptors have an important role in the tumour microenvir...

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Detalles Bibliográficos
Autores principales: Chaudhary, P, Thamake, S I, Shetty, P, Vishwanatha, J K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264449/
https://www.ncbi.nlm.nih.gov/pubmed/25321192
http://dx.doi.org/10.1038/bjc.2014.542