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Structural Analysis of How Podocytes Detach from the Glomerular Basement Membrane Under Hypertrophic Stress

Podocytes are lost by detachment from the GBM as viable cells; details are largely unknown. We studied this process in the rat after growth stimulation with FGF-2. Endothelial and mesangial cells responded by hyperplasia, podocytes underwent hypertrophy, but, in the long run, developed various chang...

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Detalles Bibliográficos
Autores principales: Kriz, Wilhelm, Hähnel, Brunhilde, Hosser, Hiltraud, Rösener, Sigrid, Waldherr, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264519/
https://www.ncbi.nlm.nih.gov/pubmed/25566184
http://dx.doi.org/10.3389/fendo.2014.00207