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The proteasome activity reporter GFP-Cl1 is degraded by autophagy in the aging model Podospora anserina
The degradation of damaged proteins is an important vital function especially during aging and stress. The ubiquitin proteasome system is one of the major cellular machineries for protein degradation. Health and longevity are associated with high proteasome activity. To demonstrate such a role in ag...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264638/ https://www.ncbi.nlm.nih.gov/pubmed/25520781 http://dx.doi.org/10.12688/f1000research.5337.1 |