Heat Shock Protein-90 Inhibitors Enhance Antigen Expression on Melanomas and Increase T Cell Recognition of Tumor Cells

In an effort to enhance antigen-specific T cell recognition of cancer cells, we have examined numerous modulators of antigen-expression. In this report we demonstrate that twelve different Hsp90 inhibitors (iHsp90) share the ability to increase the expression of differentiation antigens and MHC Clas...

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Detalles Bibliográficos
Autores principales: Haggerty, Timothy J., Dunn, Ian S., Rose, Lenora B., Newton, Estelle E., Pandolfi, Franco, Kurnick, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264751/
https://www.ncbi.nlm.nih.gov/pubmed/25503774
http://dx.doi.org/10.1371/journal.pone.0114506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264751/
https://www.ncbi.nlm.nih.gov/pubmed/25503774
http://dx.doi.org/10.1371/journal.pone.0114506

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