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Heat Shock Protein-90 Inhibitors Enhance Antigen Expression on Melanomas and Increase T Cell Recognition of Tumor Cells

In an effort to enhance antigen-specific T cell recognition of cancer cells, we have examined numerous modulators of antigen-expression. In this report we demonstrate that twelve different Hsp90 inhibitors (iHsp90) share the ability to increase the expression of differentiation antigens and MHC Clas...

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Detalles Bibliográficos
Autores principales:	Haggerty, Timothy J., Dunn, Ian S., Rose, Lenora B., Newton, Estelle E., Pandolfi, Franco, Kurnick, James T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264751/ https://www.ncbi.nlm.nih.gov/pubmed/25503774 http://dx.doi.org/10.1371/journal.pone.0114506

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