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Central Nervous System Effects of the Second-Generation Antihistamines Marketed in Japan -Review of Inter-Drug Differences Using the Proportional Impairment Ratio (PIR)-

BACKGROUND: Second-generation antihistamines (AHs) have, in general, fewer sedative effects than the first-generation. However, important inter-drug differences remain in the degree of cognitive and/or psychomotor impairment. The extent to which a particular compound causes disruption can be conveni...

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Detalles Bibliográficos
Autores principales: Isomura, Tatsuya, Kono, Takeshi, Hindmarch, Ian, Kikuchi, Norimasa, Murakami, Aya, Inuzuka, Kyoko, Kawana, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264760/
https://www.ncbi.nlm.nih.gov/pubmed/25501360
http://dx.doi.org/10.1371/journal.pone.0114336