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Host Genetics Predict Clinical Deterioration in HCV-Related Cirrhosis

Single nucleotide polymorphisms (SNPs) in the epidermal growth factor (EGF, rs4444903), patatin-like phospholipase domain-containing protein 3 (PNPLA3, rs738409) genes, and near the interleukin-28B (IL28B, rs12979860) gene are linked to treatment response, fibrosis, and hepatocellular carcinoma (HCC...

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Detalles Bibliográficos
Autores principales: King, Lindsay Y., Johnson, Kara B., Zheng, Hui, Wei, Lan, Gudewicz, Thomas, Hoshida, Yujin, Corey, Kathleen E., Ajayi, Tokunbo, Ufere, Nneka, Baumert, Thomas F., Chan, Andrew T., Tanabe, Kenneth K., Fuchs, Bryan C., Chung, Raymond T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264769/
https://www.ncbi.nlm.nih.gov/pubmed/25504078
http://dx.doi.org/10.1371/journal.pone.0114747