REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells

We describe a novel approach named REAL-Select for the non-covalent display of IgG-molecules on the surface of yeast cells for the purpose of antibody engineering and selection. It relies on the capture of secreted native full-length antibodies on the cell surface via binding to an externally immobi...

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Detalles Bibliográficos
Autores principales: Rhiel, Laura, Krah, Simon, Günther, Ralf, Becker, Stefan, Kolmar, Harald, Hock, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264850/
https://www.ncbi.nlm.nih.gov/pubmed/25501029
http://dx.doi.org/10.1371/journal.pone.0114887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264850/
https://www.ncbi.nlm.nih.gov/pubmed/25501029
http://dx.doi.org/10.1371/journal.pone.0114887

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