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REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells
We describe a novel approach named REAL-Select for the non-covalent display of IgG-molecules on the surface of yeast cells for the purpose of antibody engineering and selection. It relies on the capture of secreted native full-length antibodies on the cell surface via binding to an externally immobi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264850/ https://www.ncbi.nlm.nih.gov/pubmed/25501029 http://dx.doi.org/10.1371/journal.pone.0114887 |