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Role of IL-1β in Experimental Cystic Fibrosis upon P. aeruginosa Infection

Cystic fibrosis is associated with increased inflammatory responses to pathogen challenge. Here we revisited the role of IL-1β in lung pathology using the experimental F508del-CFTR murine model on C57BL/6 genetic background (Cftr (tm1eur) or d/d), on double deficient for d/d and type 1 interleukin-1...

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Detalles Bibliográficos
Autores principales: Palomo, Jennifer, Marchiol, Tiffany, Piotet, Julie, Fauconnier, Louis, Robinet, Marieke, Reverchon, Flora, Le Bert, Marc, Togbe, Dieudonnée, Buijs-Offerman, Ruvalic, Stolarczyk, Marta, Quesniaux, Valérie F. J., Scholte, Bob J., Ryffel, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264861/
https://www.ncbi.nlm.nih.gov/pubmed/25500839
http://dx.doi.org/10.1371/journal.pone.0114884