Cargando…
Functional and Evolutionary Significance of Human MicroRNA Seed Region Mutations
MicroRNAs have emerged in recent years as important regulators of cell function in both normal and diseased cells. MiRNAs coordinately regulate large suites of target genes by mRNA degradation and/or translational inhibition. The mRNA target specificities of miRNAs in animals are primarily encoded w...
Autores principales: | Hill, Christopher G., Jabbari, Neda, Matyunina, Lilya V., McDonald, John F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264867/ https://www.ncbi.nlm.nih.gov/pubmed/25501359 http://dx.doi.org/10.1371/journal.pone.0115241 |
Ejemplares similares
-
Transcriptional override: a regulatory network model of indirect responses to modulations in microRNA expression
por: Hill, Christopher G, et al.
Publicado: (2014) -
Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity
por: Mezencev, Roman, et al.
Publicado: (2016) -
The effects of MicroRNA transfections on global patterns of gene expression in ovarian cancer cells are functionally coordinated
por: Shahab, Shubin W, et al.
Publicado: (2012) -
Evidence for the Complexity of MicroRNA-Mediated Regulation in Ovarian Cancer: A Systems Approach
por: Shahab, Shubin W., et al.
Publicado: (2011) -
Evidence for the role of microRNA 374b in acquired cisplatin resistance in pancreatic cancer cells
por: Schreiber, R, et al.
Publicado: (2016)