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Effects of Inflammation on Hippocampus and Substantia Nigra Responses to Novelty in Healthy Human Participants

Humans are naturally inquisitive. This tendency is adaptive, aiding identification of potentially valuable novel outcomes. The dopaminergic substantia nigra (SN) is implicated in the drive to explore novel stimuli and situations. However, infection and inflammation inhibit the motivation to seek out...

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Detalles Bibliográficos
Autores principales: Harrison, Neil A, Cercignani, Mara, Voon, Valerie, Critchley, Hugo D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264953/
https://www.ncbi.nlm.nih.gov/pubmed/25154706
http://dx.doi.org/10.1038/npp.2014.222