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Calcium-sensing receptor (CaSR) as a novel target for ischemic neuroprotection

OBJECT: Ischemic brain injury is the leading cause for death and long-term disability in patients who suffer cardiac arrest and embolic stroke. Excitotoxicity and subsequent Ca(2+)-overload lead to ischemic neuron death. We explore a novel mechanism concerning the role of the excitatory extracellula...

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Detalles Bibliográficos
Autores principales: Kim, Jong Youl, Ho, Hanson, Kim, Nuri, Liu, Jialing, Tu, Chia-Ling, Yenari, Midori A, Chang, Wenhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265057/
https://www.ncbi.nlm.nih.gov/pubmed/25540800
http://dx.doi.org/10.1002/acn3.118