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Type I interferon rapidly restricts infectious hepatitis C virus particle genesis

Interferon-alpha (IFNα) has been used to treat chronic hepatitis C virus (HCV) infection for over 20 years with varying efficacy, depending on the infecting viral genotype. The mechanism of action of IFNα is not fully understood, but is thought to target multiple stages of the HCV lifecycle, inhibit...

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Detalles Bibliográficos
Autores principales: Meredith, Luke W, Farquhar, Michelle J, Tarr, Alexander W, McKeating, Jane A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265257/
https://www.ncbi.nlm.nih.gov/pubmed/25066844
http://dx.doi.org/10.1002/hep.27333