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Discovery of rare mutations in extensively pooled DNA samples using multiple target enrichment

Chemical mutagenesis is routinely used to create large numbers of rare mutations in plant and animal populations, which can be subsequently subjected to selection for beneficial traits and phenotypes that enable the characterization of gene functions. Several next-generation sequencing (NGS)-based t...

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Detalles Bibliográficos
Autores principales: Chi, Xu, Zhang, Yingchun, Xue, Zheyong, Feng, Laibao, Liu, Huaqing, Wang, Feng, Qi, Xiaoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265296/
https://www.ncbi.nlm.nih.gov/pubmed/24602056
http://dx.doi.org/10.1111/pbi.12174