Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway

BACKGROUND: Intrahepatic cholangiocarcinoma (IHCC) is the second most frequent primary malignant liver tumor following hepatocellular carcinoma. It is a highly fatal disease and has few therapeutics. The CXC chemokine ligand-12 (CXCL12)/CXC chemokine receptor type 4 (CXCR4) axis has been shown to be...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Shengqiang, Wang, Jing, Qin, Chengyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265318/
https://www.ncbi.nlm.nih.gov/pubmed/25471741
http://dx.doi.org/10.1186/s13046-014-0103-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265318/
https://www.ncbi.nlm.nih.gov/pubmed/25471741
http://dx.doi.org/10.1186/s13046-014-0103-8

Ejemplares similares