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Osteopontin Expression in the Brain Triggers Localized Inflammation and Cell Death When Immune Cells Are Activated by Pertussis Toxin

Upregulation of osteopontin (OPN) is a characteristic of central nervous system pathologies. However, the role of OPN in inflammation is still controversial, since it can both prevent cell death and induce the migration of potentially damaging inflammatory cells. To understand the role of OPN in inf...

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Detalles Bibliográficos
Autores principales: Marcondes, Maria Cecilia Garibaldi, Ojakian, Ryan, Bortell, Nikki, Flynn, Claudia, Conti, Bruno, Fox, Howard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265371/
https://www.ncbi.nlm.nih.gov/pubmed/25525298
http://dx.doi.org/10.1155/2014/358218