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De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets
BACKGROUND: In eukaryotes, transcriptional regulation is usually mediated by interactions of multiple transcription factors (TFs) with their respective specific cis-regulatory elements (CREs) in the so-called cis-regulatory modules (CRMs) in DNA. Although the knowledge of CREs and CRMs in a genome i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265420/ https://www.ncbi.nlm.nih.gov/pubmed/25442502 http://dx.doi.org/10.1186/1471-2164-15-1047 |