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Haptoglobin Duplicon, Hemoglobin, and Vitamin C: Analyses in the British Women's Heart and Health Study and Caerphilly Prospective Study

Background. Haptoglobin acts as an antioxidant by limiting peroxidative tissue damage by free hemoglobin. The haptoglobin gene allele Hp2 comprises a 1.7 kb partial duplication. Relative to allele Hp1, Hp2 carriers form protein multimers, suboptimal for hemoglobin scavenging. Objective. To examine t...

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Detalles Bibliográficos
Autores principales: Guthrie, Philip A. I., Abdollahi, Mohammad R., Gaunt, Tom, Lawlor, Debbie A., Ben-Shlomo, Yoav, Gallacher, John, Davey Smith, George, Day, Ian N. M., Rodriguez, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265517/
https://www.ncbi.nlm.nih.gov/pubmed/25525287
http://dx.doi.org/10.1155/2014/529456