Cargando…

Haptoglobin Duplicon, Hemoglobin, and Vitamin C: Analyses in the British Women's Heart and Health Study and Caerphilly Prospective Study

Background. Haptoglobin acts as an antioxidant by limiting peroxidative tissue damage by free hemoglobin. The haptoglobin gene allele Hp2 comprises a 1.7 kb partial duplication. Relative to allele Hp1, Hp2 carriers form protein multimers, suboptimal for hemoglobin scavenging. Objective. To examine t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guthrie, Philip A. I., Abdollahi, Mohammad R., Gaunt, Tom, Lawlor, Debbie A., Ben-Shlomo, Yoav, Gallacher, John, Davey Smith, George, Day, Ian N. M., Rodriguez, Santiago
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265517/ https://www.ncbi.nlm.nih.gov/pubmed/25525287 http://dx.doi.org/10.1155/2014/529456

Ejemplares similares

Sleep and the risk of cognitive impairment and dementia: further insights from the Caerphilly Prospective Study
por: Selwood, James, et al.
Publicado: (2021)

Diurnal cortisol patterns are associated with physical performance in the Caerphilly Prospective Study
por: Gardner, Michael P, et al.
Publicado: (2011)

Healthy Lifestyles Reduce the Incidence of Chronic Diseases and Dementia: Evidence from the Caerphilly Cohort Study
por: Elwood, Peter, et al.
Publicado: (2013)

Predictors and prognosis of population-based subjective cognitive decline: longitudinal evidence from the Caerphilly Prospective Study (CaPS)
por: Ball, Harriet A, et al.
Publicado: (2023)

Associations of Insulin and Insulin-Like Growth Factors with Physical Performance in Old Age in the Boyd Orr and Caerphilly Studies
por: Birnie, Kate, et al.
Publicado: (2012)

Homogeneous Assay of rs4343, an ACE I/D Proxy, and an Analysis in the British Women’s Heart and Health Study (BWHHS)
por: Abdollahi, Mohammad Reza, et al.
Publicado: (2008)

Troponin and BNP are markers for subsequent non-ischaemic congestive heart failure: the Caerphilly Prospective Study (CaPS)
por: Patterson, Christopher C, et al.
Publicado: (2018)

Which biomarkers are predictive specifically for cardiovascular or for non-cardiovascular mortality in men? Evidence from the Caerphilly Prospective Study (CaPS)
por: Patterson, Christopher C., et al.
Publicado: (2015)

Associations of Infant Nutrition with Insulin Resistance Measures in Early Adulthood: Evidence from the Barry-Caerphilly Growth (BCG) Study
por: Williams, Dylan M., et al.
Publicado: (2012)

Molecular and Population Analysis of Natural Selection on the Human Haptoglobin Duplication
por: Rodriguez, Santiago, et al.
Publicado: (2012)

Urban built environment configuration and psychological distress in older men: Results from the Caerphilly study
por: Sarkar, Chinmoy, et al.
Publicado: (2013)

Human subtelomeric duplicon structure and organization
por: Ambrosini, Anthony, et al.
Publicado: (2007)

Neighbourhood green space, physical function and participation in physical activities among elderly men: the Caerphilly Prospective study
por: Gong, Yi, et al.
Publicado: (2014)

Amplification ratio control system for copy number variation genotyping
por: Guthrie, Philip A. I., et al.
Publicado: (2011)

Haptoglobin Genotype Is a Determinant of Hemoglobin Adducts and Vitamin E Content in HDL
por: Goldenstein, Hagit, et al.
Publicado: (2018)

Molecular Modeling of the Human Hemoglobin-Haptoglobin Complex Sheds Light on the Protective Mechanisms of Haptoglobin
por: Nantasenamat, Chanin, et al.
Publicado: (2013)

Evolutionary analysis of the highly dynamic CHEK2 duplicon in anthropoids
por: Münch, Claudia, et al.
Publicado: (2008)

Vitamin D intake and risk of CVD and all-cause mortality: evidence from the Caerphilly Prospective Cohort Study
por: Guo, Jing, et al.
Publicado: (2017)

Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol
por: Guthrie, Philip A.I., et al.
Publicado: (2012)

A Novel Framework for the Identification and Analysis of Duplicons between Human and Chimpanzee
por: Chuang, Trees-Juen, et al.
Publicado: (2013)

Human core duplicon gene families: game changers or game players?
por: Bekpen, Cemalettin, et al.
Publicado: (2019)

Dietary Patterns in Relation to Cardiovascular Disease Incidence and Risk Markers in a Middle-Aged British Male Population: Data from the Caerphilly Prospective Study
por: Mertens, Elly, et al.
Publicado: (2017)

Hemoglobin-Conjugated Gold Nanoclusters for Qualitative Analysis of Haptoglobin Phenotypes
por: Tan, Shih-Hua, et al.
Publicado: (2020)

The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis
por: Lawlor, Debbie A, et al.
Publicado: (2004)

The intrathecal CD163-haptoglobin–hemoglobin scavenging system in subarachnoid hemorrhage
por: Galea, James, et al.
Publicado: (2012)

Mechanisms of haptoglobin protection against hemoglobin peroxidation triggered endothelial damage
por: Schaer, C A, et al.
Publicado: (2013)

The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging
por: Thomsen, Jens Haugbølle, et al.
Publicado: (2013)

Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders
por: Smith, Ann, et al.
Publicado: (2015)

Modeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species–pharmacokinetic and therapeutic implications
por: Boretti, Felicitas S., et al.
Publicado: (2014)

Erythropoietin, ferritin, haptoglobin, hemoglobin and transferrin receptor in metabolic syndrome: a case control study
por: Hämäläinen, Päivi, et al.
Publicado: (2012)

Genetic determinants of circulating haptoglobin concentration
por: Kazmi, Nabila, et al.
Publicado: (2019)

Adversity in Childhood and Measures of Aging in Midlife: Findings From a Cohort of British Women
por: Anderson, Emma L., et al.
Publicado: (2017)

Partial duplication of the APBA2 gene in chromosome 15q13 corresponds to duplicon structures
por: Sutcliffe, James S, et al.
Publicado: (2003)

Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus
por: Maggiolini, Flavia A. M., et al.
Publicado: (2019)

A wealth of genotype-specific proteoforms fine-tunes hemoglobin scavenging by haptoglobin
por: Tamara, Sem, et al.
Publicado: (2020)

Evolutionary consequences of a large duplication event in Trypanosoma brucei: Chromosomes 4 and 8 are partial duplicons
por: Jackson, Andrew P
Publicado: (2007)

Development and Validation of a Path Length Calculation for Carotid–Femoral Pulse Wave Velocity Measurement: A TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture
por: Weir-McCall, Jonathan R., et al.
Publicado: (2018)

Haptoglobin treatment prevents cell-free hemoglobin exacerbated mortality in experimental rat sepsis
por: Schaer, Christian A., et al.
Publicado: (2021)

Perceptions of the neighbourhood environment and self rated health: a multilevel analysis of the Caerphilly Health and Social Needs Study
por: Poortinga, Wouter, et al.
Publicado: (2007)

Adherence to a healthy diet in relation to cardiovascular incidence and risk markers: evidence from the Caerphilly Prospective Study
por: Mertens, Elly, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_q789dtv32hfueehteao16065c8